LTP (long-term potentiation). Mechanism of LTP (long-term potentiation), which plays a role in learning. Stage 1 (See images no. 11969 05 and 11970 05 for stages 2 and 3). In response to a stimulus (sight, taste, touch, etc.), an electrical signal is produced which triggers the release of massive quantities of glutamate (purple triangles) by the presynaptic element. This in turn triggers a massive release of calcium (red spheres) in the dendrite (postsynaptic element), setting off a biochemical chain reaction which increases synaptic efficacy. In the short term, this translates into enhanced permeability and lengthened opening times for postsynaptic ionic channels as well as an increase in the number of presynaptic glutamate vesicles.
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