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Human chromosomes. The human karyotype is composed of 23 pairs of chromosomes, including 1 pair of sexual chromosomes (XX for the female, XY for the male). The chromosomes carry genetic information, formed by a long DNA molecule, associated with proteins. They can be organized in seven groups (A through G) according to the Denver classification (by size and position of the centromere as determined during mitotic metaphase). Illustration of microscopy. Magnification: 3900x per 10 cm.